Should I call the MSPCA? Can they help?

A close friend of mine has an APBT/Mastiff whom I am very concerned about. I cared for him as a pup, and he had a great disposition, but under the care of my friend he has grown anxious and agressive toward strangers. I could easily point out the mistakes she's made raising him; Prong collar 24/7, no walks, little exercise, no socialization, no training, use of physical discipline, unaltered...and all of this has lead to him being anxious and wary. My friend does not seem like she is going to change her ways, and I'm worried that this dog will end up nothing but a loaded gun. Due to the level of animal agression in this dog, I cannot take him myself without risking the health and happiness of my dogs....but I still think something must be done. He is in great physical condition and recieves proper veterinary care, so will the MSPCA be able to do anything? Or does there need to be signs of physical abuse before they will sieze the animal? Can I report her anonymously?